CTCAE RápidoAdverse event grades · CTCAE v6.0
Código Onco

Neoplasms benign, malignant and unspecified (incl cysts and polyps)

The 10 CTCAE v6.0 adverse events in Neoplasms benign, malignant and unspecified (incl cysts and polyps), with grades 1 to 5.

Differentiation syndrome

Neoplasms benign, malignant and unspecified (incl cysts and polyps)New in v6.0
  1. G1Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated
  2. G2Moderate; minimal, local, or noninvasive intervention indicated; limiting age appropriate instrumental ADL
  3. G3Severe or medically significant but not immediately life-threatening; limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
  4. G4Life-threatening consequences; urgent intervention indicated
  5. G5Death
Definition and note

DefinitionA potentially fatal complication of treatment in certain molecular subgroups of leukemia characterized by fever, rash, dyspnea and/or hypoxia, pulmonary infiltrates, peripheral edema with rapid weight gain, pleuropericardial effusion, acute renal failure, disseminated intravascular coagulation (DIC), bone pain and/or hypotension.

MedDRA code (LLT): 10080638 · CTCAE v6.0 (NCI), original English text.

Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify

Neoplasms benign, malignant and unspecified (incl cysts and polyps)
  1. G1Asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated
  2. G2Moderate; minimal, local or noninvasive intervention indicated; limiting instrumental ADL or mild/moderate impact on age-appropriate normal daily activity (pediatric)
  3. G3Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated; limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
  4. G4Life-threatening consequences; urgent intervention indicated
  5. G5Death
Definition and note

MedDRA code (LLT): 10029104 · CTCAE v6.0 (NCI), original English text.

Retinoic acid syndrome

Neoplasms benign, malignant and unspecified (incl cysts and polyps)
  1. G1Fluid retention; <3 kg of weight gain; intervention with fluid restriction and/or diuretics indicated
  2. G2Moderate signs or symptoms; steroids indicated
  3. G3Severe symptoms; hospitalization indicated
  4. G4Life-threatening consequences; ventilatory support indicated
  5. G5Death
Definition and note

DefinitionA disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid.

MedDRA code (LLT): 10038921 · CTCAE v6.0 (NCI), original English text.

Tumor pain

Neoplasms benign, malignant and unspecified (incl cysts and polyps)
  1. G1Mild pain
  2. G2Moderate pain; limiting instrumental ADL or mild/moderate impact on age-appropriate normal daily activity (pediatric)
  3. G3Severe pain; limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
  4. G4Not applicable
  5. G5Not applicable
Definition and note

DefinitionA disorder characterized by a sensation of marked discomfort from a neoplasm that may be pressing on a nerve, blocking blood vessels, inflamed or fractured from metastasis.

Navigational noteRecord final diagnosis/cause once determined.

MedDRA code (LLT): 10045158 · CTCAE v6.0 (NCI), original English text.

From the same authorCódigo OncoCódigo Onco (in Portuguese): Brazilian public health system (SUS) codes for systemic cancer treatment.