Anaphylaxis
- G1Not applicable
- G2Not applicable
- G3Symptomatic bronchospasm, with or without urticaria; parenteral intervention indicated; allergy-related edema/angioedema; hypotension
- G4Life-threatening consequences; urgent intervention indicated
- G5Death
Definition and note
DefinitionA disorder characterized by an acute inflammatory reaction resulting from the release of histamine and histamine-like substances from mast cells, causing a hypersensitivity immune response. Clinically, it presents with breathing difficulty, dizziness, hypotension, cyanosis and loss of consciousness and may lead to death.
Navigational noteIf related to infusion, consider Injury, poisoning and procedural complications: Infusion related reaction. Do not report both.
MedDRA code (LLT): 10002218 · CTCAE v6.0 (NCI), original English text.