Sinusoidal obstruction syndrome
- G1Not applicable
- G2Blood bilirubin 2 - 5 mg/dL; minor interventions required (i.e., blood product, diuretic, oxygen)
- G3Blood bilirubin >5 mg/dL; coagulation modifier indicated (e.g., defibrotide); reversal of flow on ultrasound
- G4Life-threatening consequences (e.g., ventilatory support, dialysis, plasmapheresis, peritoneal drainage)
- G5Death
Definition and note
DefinitionA disorder characterized by severe hepatic injury as a result of the blood vessels of the liver becoming inflamed and/or blocked.
MedDRA code (LLT): 10063675 · CTCAE v6.0 (NCI), original English text.